Hop right into a moto-taxi and when they do not know 'Tambopata Hostel', or 'avenida 26 de deciembre', just request the Plaza de Armas (principal city sq.); carry on past the main square on the right hand aspect, and on reaching the best corner check with the driver to show correct (derecha) and proceed up to the last street (avenida 26 de deciembr